Principal Clinical Scientist

Principal Clinical Scientist (AI Training)

About the Role

What if your years of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research — helping ensure the AI systems shaping the future of medicine actually get the science right.

This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful, high-impact work on their own terms.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
• Provide expert feedback that directly improves how AI models reason about clinical data, trial outcomes, and evidence quality
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing clinical trial protocols for regulatory submission (FDA, EMA, or equivalent)
• Deep expertise interpreting clinical data in the context of regulatory review and submission
• Strong background in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold scientific work to a high standard
• Able to communicate complex clinical concepts clearly in written feedback
• Comfortable working independently in a remote, task-based environment

Nice to Have

• Prior experience with data annotation, data quality evaluation, or AI training workflows
• Background in pharmacovigilance, medical affairs, or clinical operations
• Familiarity with AI tools or research platforms as an end user
• Experience across multiple therapeutic areas or trial phases

Why Join Us

• Work directly on frontier AI systems impacting clinical and biomedical research worldwide
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Influence how AI understands and evaluates real-world clinical evidence at a foundational level
• Potential for ongoing work and contract extension as new projects launch